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NameWen-Huang Peng
DesignationProfessor
DepartmentPharmaceutical Sciences
Countrychina
Address

 China Medical University, 91, Hsueh Shih Road, Taichung, 40402, Taiwan, Republic of China

 


Biography :

■PRESENT POSITION
1. Professor:Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Biopharmaceutical and Food Sciences, China Medical University.

■PROFESSIONAL EXPERIENCE
1. Assistant, Integrated Chinese and Western Medical Association(1996)

■HONOURS
1. Hong-Yuan Hsih Academy of Chinese Medicine, (2007)

Research :

1. Chinese herb combination for treatment and prevention of memory consolidation. (Patent No: I259771, Taiwan)(2006-2023)

2. Composition for treating diseased liver.(Patent No: 7,150,886,U.S.A.)(2006.12 ~ )

3. Methods for producing extracts of Boehmeria frutescens Thunberg or Boehmeria nivea for hepatitis treatment. (Patent No: 7,431,946 B2, USA)(2008.10-)

4. A medical doctor's prescription for a liver disease treatment method and a method for producing the same. (Patent No: Charter No. 4220426, Japan) (2008.11-)

 

Education:

1. B.S. in Pharmacy:School of Pharmacy, China Medical College, Taichung, Taiwan, Republic of China(1982~1987)

2. M.S. in Pharmacology:Graduate Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan,Republic of China(1987~1989)

3. Ph.D. in Pharmacology:Graduate Institute of Chinese Pharmaceutical Sciences and Chinese Medicine, China Medical College, Taichung, Taiwan, Republic of China(1989~1991)

Research Interests:

  • Pharmacology on Chinese Herb
  • Cognitive Pharmacology on Chinese Herb
  • Behavioral Pharmacology
  • Psychopharmacology
  • Neuropharmacology

List of Publications:

1. Yung-Chieh Tsai, Bo-Cheng Yang, Peng, Wen-Huang, Yen-Mei Lee, Mao-Hsiung Yen, Pao-Yun Cheng. Heme oxygenase-1 mediates anti-adipogenesis effect of raspberry ketone in 3T3-L1 cells. PHYTOMEDICINE 2017 Jul, 31:11-17. 

2. Keng-Fan Liu, Yingxiao Li, Kai-Chung Cheng, Chao Chin Hsu, Juei-Tang Cheng, Peng, Wen-Huang*. Changes in PPAR delta expression in a rat model of stress-induced depression. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 2017 Jun, 44(6):664-670. 

3. Jen-Chieh Tsai, Chuan-Sung Chiu, Yun-Chieh Chen, Meng-Shiou Lee, Xiu-Ying Hao, Ming-TsuenHsieh, Chun-Pin Kao, Wen-Huang Peng*. Hepatoprotective effect of Coreopsis tinctoria flowers against carbon tetrachloride-induced liver damage in mice. BMC Complementary and Alternative Medicine 2017 Apr, 17(139):

4. Yung-Jia Chiu, Chou, Shen-Chieh, Chuan-Sung Chiu, Chun-Pin Kao, Kun-Chang W, Chen, Chao-Jung, Jen-Chieh Tsai, Peng, Wen-Huang*. Hepatoprotective effect of the ethanol extract of Polygonum orientale on carbon tetrachloride-induced acute liver injury in mice. JOURNAL OF FOOD AND DRUG ANALYSIS,2017 Apr

5. Chang Ching-Wen, Chen Yun-Chieh, Lin Yu-Chin, Wen-Huang Peng*. p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models,Journal of Natural Medicines,2017 Jan

6. Chao, Jung, Yuntao Dai, Hao-Yuan Cheng, Wing Lam, Yung-Chi Cheng, Ke Li, Wen-Huang Peng, Li-Heng Pao, Ming-Tsuen Hsieh, Xue-Mei Qin*, Meng-Shiou Lee*. Improving the Concentrations of the Active Components in the Herbal Tea Ingredient, Uraria crinita: The Effect of Post-harvest Oven-drying Processing,Scientific Reports,2017 Jan,7():38763

7. Wen-Huang Peng, Yi-Wen Chen, Meng-Shiou Lee, Wen-Te Chang, Jen-Chieh Tsai, Ying-Chin Lin, Lin, Ming-Kuem*. Hepatoprotective Effect of Cuscuta campestris Yunck. Whole Plant on Carbon Tetrachloride Induced Chronic Liver Injury in Mice,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2016 Dec, 17: 2056-2067.

8. Jia-HungYe, Chao, Jung, Ming-Ling Chang, Wen-Huang Peng, Hao-YuanCheng, Jiunn-Wang Liao, Li-Heng Pao*. Pentoxifylline ameliorates non-alcoholic fatty liver disease in hyperglycaemic and dyslipidaemic mice by upregulating fatty acid β-oxidation,Scientific Reports,2016 Sep.

9. Der-Shiang Tsai, Mei-Hsuen Huang, Yuan-Shiun Chang, Tsai-Chung Li, Wen-Huang Peng. The use of Chinese herbal medicines associated with reduced mortality in chronic hepatitis B patients receiving lamivudine treatment. Journal of Ethnopharmacology 2015; 174:161-167.

10. Chia-Yu Liu, Yung-Jia Chiu, Chao-Lin Kuo, Tzu-Mei Chien, Lung-Yuan Wu, Wen-Huang Peng. Analgesic and Anti-inflammatory Activities of the Ethanol Extract of Taxillus tsaii Chiu in Mice. Drug Dev Res. 2015;76(4):176-84.

11. Guan-Hua Lai, Jung Chao, Ming-Kuem Lin, Wen-Te Chang, Wen-Huang Peng, Fang-Chun Sun, Meng-Shiou Lee. Rapid and Sensitive Identification of the Herbal Tea Ingredient Taraxacum formosanum using Loop-Mediated Isothermal Amplification. IJMS, 2015;16(1):1562-75. 

12. Der-Shiang Tsai ; Mei-Hsuen Huang, Tsai JC, Yuan-Shiun Chang, Chiu YJ, Lin YC, Wu LY, Peng WH. Analgesic and Anti-Inflammatory Activities of Rosa taiwanensis Nakai in Mice. J Med Food. 2015;18(5):592-600.

13. Der-Shiang Tsai, Yuan-Shiun Chang, Tsai-Chung Li, Wen-Huang Peng. Prescription pattern of Chinese herbal products for hypertension in Taiwan: A population-based study. Journal of Ethnopharmacology 2014; 155:1534-1540.

14. Jung Chao, Teh-Ia Huo, Ying-Ling Chang, Hao-Yuan Cheng, Jen-Chieh Tsai, Jiunn-Wang Liao, Meng-Shiou Lee, Xue-Mei Qin, Ming-Tsuen Hsieh, Li-Heng Pao, Wen-Huang Peng. Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice. PLOS ONE 2014, DOI: 10.1371/journal.pone.0096969.

15. Jung Chao, Teh-Ia Huo, Hao-Yuan Cheng, Jen-Chieh Tsai, Jiunn-Wang Liao, Meng-Shiou Lee, Xue-Mei Qin, Ming-Tsuen Hsieh, Li-Heng Pao, Wen-Huang Peng. Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice. PLOS ONE 2014, 9(6): e96969.

16. Jung-Chun Liao, Wen-Te Chang, Meng-Shiou Lee, Yung-Jia Chiu, Wei-Kai Chao, Ying-Chih Lin, Ming-Kuem Lin, and Wen-Huang Peng*. Antinociceptive and Anti-Inflammatory Activities of Cuscuta chinensis Seeds in Mice. The American Journal of Chinese Medicine, 2014, 42(1): 223–242.

17. Kun-Ning Chen, Wen-Huang Peng, Chien-Wen Hou, Chung-Yu Chen, Hwei-Hsien Chen, Chia-Hua Kuo, Mallikarjuna Korivi. Codonopsis javanica root extracts attenuates hyperinsulinemia and lipid peroxidation in fructose-fed insulin resistant rats. Journal of Food and Drug Analysis 2013, (in press). 

18. Jung-Chun Liao, Jen-Chieh Tsai, Wen-Huang Peng, Yung-Jia Chiu, Ping-Jyun Sung, Minoru Tsuzoki, Yueh-Hsiung Kuo. Anti-Inflammatory Activity of N-(3-Florophenyl)ethylcaffeamide in Mice,INTERNATIONAL Journal of MOLECULAR SCIENCES,2013, 14: 15199-15211.

19. Jung Chao, Jiunn-Wang Liao, Wen-Huang Peng, Meng-Shiou Lee, Li-Heng Pao and Hao-Yuan Cheng. Antioxidant, Analgesic, Anti-Inflammatory, and Hepatoprotective Effects of the Ethanol Extract of Mahonia oiwakensis Stem. Int. Journal of Mol. Sci. 2013, 14, 2928-2945; doi:10.3390/ijms14022928.

20. Chia-Yu Liu, Yung-Jia Chiu, Lung-Yuan Wu, Chao-Lin Kuo, Wen-Huang Peng*. Analgesic and Anti-inflammatory Activities of the Ethanol Extract of Taxillus sutchuenensis in Mice. African Journal of Pharmacy and Pharmacology 2013(accepted).

21. Meng-Shiou Lee, Jung Chao, Jiin-Cherng Yen, Li-Wei Lin, Fan-Shiu Tsai, Ming-Tsuen Hsieh, Wen-Huang Peng and Hao-Yuan Cheng. Schizandrin Protects Primary Rat Cortical Cell Cultures fromGlutamate-Induced Apoptosis by Inhibiting Activation of the MAPK Family and the Mitochondria Dependent Pathway. Molecules 2013, 18, 354-372; doi:10.3390/molecules18010354.

22. Shen-Chieh Chou, Yung-Jia Chiu, Chao-Jung Chen, Ying-Chih Lin, Chung-Hao Wu, Chien-Ti Chao, Ching-Wen Chang, Wen-Huang Peng. Analgesic and Anti-inflammatory Activities of Ethanolic Extract of Artemisia morrisonensis Hayata in mice. Evidence-based Complementary and Alternative Medicine 2012, doi:10.1155/2012/138954.

23. Chu-Hui Chiang, Tsong-Ann Yu, Shu-Fang Lo, Chao-Lin Kuo, Wen-Huang Peng, Hsin-Sheng Tsay. Molecular Authentication of Dendrobium Species by Multiplex Polymerase Chain Reaction and Amplification Refractory Mutation System Analysis. Journal of AMER. SOC. HORT. SCI. 137(6):438–444. 2012.

24. Ching-Wen Chang, Wen-Te Chang, Jung-Chun Liao, Yung-Jia Chiu, Ming-Tsuen Hsieh, Wen-Huang Peng and Yu-Chin Lin. Analgesic and Anti-inflammatory Activities of Methanol Extract of Cissus repens in Mice. Evidence-based Complementary and Alternative Medicine 2012, doi:10.1155/2012/135379.

25. Chi-Ren Liao, Chun-Pin Kao, Wen-Huang Peng, Yuan-Shiun Chang, Shang-Chih Lai and Yu-Ling Ho. Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice. Evidence-based Complementary and Alternative Medicine 2012, DOI:10.1155/2012/340141.

26. Chi-Ren Liao, Wen-Huang Peng, Yuan-Shiun Chang, Shang-Chih Lai, Yu-Ling Ho. Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice. The American journal of Chinese medicine 2012;40(3):581-97. 

27. Chia-Yu Liu, Wen-Huang Peng, Jeng-Shyan Deng, Jung-Chun Liao, Ying-Chih Lin, Guan-Jhong Huang. Antioxidant, anti-inflammatory, and antiproliferative activities of Taxillus sutchuenensis. The American journal of Chinese medicine 2012;40(2):335-48.

28. Lieh-Ching Hsu, Yu-Jen Ko, Hao-Yuan Cheng, Ching-Wen Chang, Yu-Chin Lin, Ying-Hui Cheng, Ming-Tsuen Hsieh, Wen-Huang Peng. Antidepressant-like activity of the ethanolic extract from Uncaria lanosa Wallich. var. appendiculata Ridsd in the forced swimming test and in the tail suspension test in mice. Evidence-based Complementary and Alternative Medicine doi:10.1155/2012/497302, 2012. 

29. Tran Duc Dung, Hsien-Cheh Chang, Chung-Yu Chen, Wen-Huang Peng, Chang-Hai Tsai, Fuu-Jen Tsai, Wei-Wen Kuo, Li-Mien Chen, Chih-Yang Huang*. Zanthoxylum avicennae extracts induce cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells and block tumor growth in xenografted nude mice,International Journal of Molecular Medicine, 2011, 28(1):927-936.

30. Shu-Ling Liu, Ying-Chih Lin, Tai-Hung Huang, Shu-Wen Huang, Wen-Huang Peng. Anti-depressive Activity of Gardeniae Frutus and Geniposide in Mouse models of depression. African Journal of Pharmacy and Pharmacology 2011; 5(18): 1580-1588.[pdf] 

31. Jen-Chieh Tsai, Wen-Huang Peng, Chiu Tai-Hui, Shang-Chih Lai, Lee Chao-Ying. Anti-inflammatory Effects of Scoparia dulcis L. and Betulinic Acid. AMERICAN Journal of CHINESE MEDICINE 2011; 39(5): 943-956. 

32. Yung-Jia Chiu, Tai-Hung Huang, Chuan-Sung Chiu, Tsung-Chun Lu, Ya-Wen Chen, Wen-Huang Peng, Chiu-Yuan Chen. Analgesic and Anti-inflammatory Activities of the Aqueous Extract from 1 Plectranthus amboinicus (Lour.) Spreng. both in Vitro and in Vivo. Evidence-based Complementary and Alternative Medicine 2011 (Volume 2012, Article ID 508137, 11 pages, doi:10.1155/2012/508137). 

33. Yun-Chen Tien, Jung-Chun Liao, Chuan-Sung Chiu, Tai-Hung Huang, Chih-Yang Huang, Wen-Te Chang, Wen-Huang Peng. Esculetin Ameliorates Carbon Tetrachloride-Mediated Hepatic Apoptosis in Rats. International Journal of Molecular Sciences 2011, 12(6): 4053-4067. 

34. Chuan-Sung Chiu, Yung-Jia Chiu, Lung-Yuan Wu, Tsung-Chun Lu, Tai-Hung Huang, Ming-Tsuen Hsieh, Chung-Yen Lu, Wen-Huang Peng. Diosgenin ameliorates cognition deficit and attenuates oxidative damage in senescent mice induced by D-galactose. The American Journal of Chinese Medicine 2011, 39(3): 551-563.

35. Tsung-Chun Lu, Jung-Chun Liao, Tai- Hung Huang, Ying-Chih Lin, Chia-Yu Liu, Yung-Chia Chiu, Wen-Huang Peng. Analgesic and Anti-inflammatory Activities of the methanol Extract from Pogostemon cablin. Evidence-based Complementary and Alternative Medicine.Volume 2011, Article ID 671741, 9 pages (doi:10.1093/ecam/nep183).[pdf] 

36. Lung-Yuan Wu, Cheng-Wei Cheng, Yun-Chen Tien, Chao-Lin Kuo,Shu-Fung Lo4, Wen-Huang Peng. Anti-oxidative and Hepatoprotective Activities of Dendrobium Tosaense and Ephemerantha Fimbriata in Carbon Tetrachloride-Induced Acute Liver Injury. J Chin Med 2011, 22: 47-63.[pdf]. 

 

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